Vemox 500 is a drug, a semi-synthetic antibiotic of a broad spectrum of action of the penicillin group. Its pharmacological properties are close to ampicillin, but, unlike it, it has better bioavailability when taken orally. Amoxicillin, like many other beta-lactam antibiotics, is subject to beta-lactamase degradation produced by certain bacteria, so it is often used in combination with clavulanic acid, an inhibitor of such enzymes.
Indications of Vemox 500
Bacterial infections caused by sensitive microflora: infections of the respiratory tract and ENT organs (sinusitis, pharyngitis, tonsillitis, acute otitis media, bronchitis, pneumonia), urogenital system (pyelonephritis, pyelitis, cystitis, urethritis, gonorrhea, endometritis, cervicitis) (bile duct, impetigo, secondarily infected dermatosis), leptospirosis, listeriosis, Lyme disease it, endocarditis (prophylaxis), sepsis.
Dosing and Administration of Vemox 500
Vemox 500 is administered orally, before or after a meal. Adults and children over 10 years of age (with a body weight of more than 40 kg) are prescribed 0.5 g 3 times a day; in severe infection – 0.75-1 g 3 times a day.
In acute uncomplicated gonorrhea appoint 3 g once; in the treatment of women, repeated intake of this dose is recommended.
In acute infectious diseases of the gastrointestinal tract (paratyphoid, typhoid) and biliary tract, with gynecological infectious diseases adults – 1.5-2 g 3 times a day or 1-1.5 g 4 times a day.
In severe infections (meningitis, septicemia), adults – up to 6 g per day in 3-4 doses. Children – 250-500 mg 3 times a day. The duration of treatment depends on the indications and the clinical picture and is usually 5-7 days. When otitis and similar infections, children have a two-time intake of Vemox 500. In cases of chronic diseases, recurrent infections, infections of severe course, adults are prescribed 750 mg-1 g 3 times a day, children up to 60 mg / kg per day divided into 3 doses.
With leptospirosis, adults – 0.5-0.75 g 4 times a day for 6-12 days.
When listeriosis adults – 0.5 g 3 times a day for 6-12 days.
With salmonella carrying adults – 1.5-2 g 3 times a day for 2-4 weeks.
For the prevention of endocarditis with small surgical interventions for adults – 3-4 g for 1 h before the procedure. If necessary, appoint a second dose after 8-9 hours.
In children, the dose is reduced by half.
In patients with impaired renal function with creatinine clearance of 15-40 ml / min, the interval between doses is increased to 12 h; when creatinine clearance is less than 10 ml / min, the dose is reduced by 15-50%; with anuria the maximum dose of 2 g / day.